PF-CBP1 hydrochloride
CAS No. 2070014-93-4
PF-CBP1 hydrochloride ( PF CBP1 hydrochloride )
产品货号. M13218 CAS No. 2070014-93-4
A potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
生物学信息
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产品名称PF-CBP1 hydrochloride
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述A potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively.
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产品描述A potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively; displays >100-fold selectivity for the bromodomain of CBP over those of BRD4 and a panel of other proteins; reduces the expression of inflammatory cytokines by LPS-stimulated primary macrophages, also suppresses the expression of RGS4 in primary cortical neurons.
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同义词PF CBP1 hydrochloride
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通路Chromatin/Epigenetic
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靶点Bromodomain
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受体Bromodomain
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研究领域——
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适应症——
化学信息
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CAS Number2070014-93-4
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分子量525.08
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分子式C29H37ClN4O3
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 34 mg/mL
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SMILESCCCOC1=CC=C(C=C1)CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5.[H]Cl
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化学全称4-(2-(5-(3,5-dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96.
产品手册
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